Monday, 30 September 2013

NIH announces 2013 High Risk-High Reward Research Awards

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09/30/2013 11:48 AM EDT

NIH commits to 78 awards to support exceptional innovation in biomedical research.


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NGC Update Service: September 30, 2013

National Guideline Clearinghouse (NGC)

September 30, 2013


New This Week

Guideline Summaries

American College of Chest Physicians

Canadian Agency for Drugs and Technologies in Health

Canadian Task Force on Preventive Health Care

Catalan Agency for Health Information, Assessment and Quality

Centers for Disease Control and Prevention

College of Family Physicians of Canada New Developer

National Collaborating Centre for Mental Health

National Institute for Health and Care Excellence (NICE)

National Kidney Foundation

U.S. Preventive Services Task Force

Announcements

Annotated Bibliographies Feature

NGC will be retiring the Annotated Bibliographies. This feature will no longer be available after October 9th.

NGC Spotlight

See the updated Mobile Device Resources page for information on the availability of full-text guidelines and/or companion documents available in downloadable versions for smart phones and hand-held devices.

Revised Inclusion Criteria

NGC has revised its Inclusion Criteria! Visit our updated Inclusion Criteria page to see the new criteria and send us your comments.

Health Awareness Topics - October 2013

Conference News

  • The Guidelines International Network North America (G-I-N NA) continues to sponsor a monthly webinar series on topics of interest to the North American guideline community. Information on upcoming webinars, as well as audio files and slides from past webinars, is available on the G-I-N Web site.

U.S. Food and Drug Administration (FDA) Advisories

  • September 27, 2013: Tygacil (tigecycline): FDA notified health professionals and their medical care organizations of a new Boxed Warning describing an increased risk of death when intravenous Tygacil is used for FDA-approved uses as well as for non-approved uses. These changes to the Tygacil Prescribing Information are based on an additional analysis that was conducted for FDA-approved uses after FDA issuing a Drug Safety Communication about this safety concern in September 2010.
  • September 25, 2013: Arzerra (ofatumumab) and Rituxan (rituximab): FDA approved changes to the prescribing information of the immune-suppressing and anti-cancer drugs Arzerra (ofatumumab) and Rituxan (rituximab) to add new Boxed Warning information about the risk of reactivation of hepatitis B virus (HBV) infection. The revised labels also will include additional recommendations for screening, monitoring, and managing patients on these drugs to decrease this risk.

NGC's Sister Resources


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Study Evaluates Population-Wide Testing, Early Treatment for HIV Prevention

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Study Evaluates Population-Wide Testing, Early Treatment for HIV Prevention

A new study in South Africa and Zambia will assess whether house-to-house voluntary HIV testing and prompt treatment of HIV infection, along with other proven HIV prevention measures, can substantially reduce the number of new HIV infections across communities.

The trial, Population Effects of Antiretroviral Therapy to Reduce HIV Transmission (PopART), or HPTN 071, is sponsored and co-funded by NIAID.

Learn more about the PopART study.


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MedlinePlus Health News

09/30/2013 09:35 AM EDT

Source: HealthDay - Video
Related MedlinePlus Pages: Attention Deficit Hyperactivity Disorder, Child Mental Health
09/29/2013 09:00 AM EDT

Study found years of training suppressed signals of imbalance; findings could help those with chronic dizziness

HealthDay news image

Source: HealthDay
Related MedlinePlus Page: Dizziness and Vertigo
09/28/2013 02:13 AM EDT

Artist and therapy student Anna and her friends marked a birthday in New York recently with a familiar ritual: They pumped up the electronic music, danced, and celebrated with a special guest called Molly.



Source: Reuters Health
Related MedlinePlus Page: Club Drugs
09/27/2013 04:00 PM EDT

Alone or combined with alcohol, study finds it multiplies the risk for road fatalities

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Drug Abuse, Impaired Driving
09/27/2013 04:00 PM EDT

Boosting exercise, limiting caffeine and reducing video games at bedtime are important

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Autism, Parenting, Sleep Disorders
09/27/2013 03:12 PM EDT

Private insurance companies across the U.S. pay doctors dramatically different amounts for the same routine office visits and services, according to a new study.
Source: Reuters Health
Related MedlinePlus Pages: Health Insurance, Health Occupations
09/27/2013 02:27 PM EDT

A new generation of drugs designed to trigger the immune system to fight cancer is offering the prospect of a "clinical cure" for some melanoma skin cancer patients who until a few years ago were more likely to be facing a swift death.
Source: Reuters Health
Related MedlinePlus Page: Melanoma
09/27/2013 02:00 PM EDT

Low-sodium diet lowered high blood pressure after 3 weeks

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Dietary Sodium, Diets, Heart Failure
09/27/2013 02:00 PM EDT

Canadian researchers develop model for assessing infants' risk of complications

HealthDay news image

Source: HealthDay
Related MedlinePlus Page: Premature Babies
09/27/2013 02:00 PM EDT

Study of mice builds on landmark findings from 1990s, researcher says

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Alzheimer's Disease, Genes and Gene Therapy
09/27/2013 02:00 PM EDT

New finding paves way for improved therapy for kids with neurological disorders, researchers say

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Neuromuscular Disorders, Teen Development
09/27/2013 12:00 PM EDT

Accumulated knowledge helped seniors outperform young adults when faced with economic choices

HealthDay news image

Source: HealthDay
Related MedlinePlus Page: Seniors' Health
09/27/2013 12:00 PM EDT

Regular consumption in childhood tied to 39 percent lower odds of benign breast disease by age 30

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Breast Cancer, Breast Diseases, Child Nutrition
09/27/2013 12:00 PM EDT

Current smokers had highest rates of pneumonia, infection

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: After Surgery, Colonic Diseases, Smoking
09/27/2013 09:00 AM EDT

Little-used depression drug shows early promise in lab, mice studies

HealthDay news image

Source: HealthDay
Related MedlinePlus Pages: Antidepressants, Lung Cancer


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Plant Pigments Might Help Protect Your Bones / Dark Chocolate: A Valentine for Your Health / Omega-3s in Fish May Help Slow Biological Aging

Tufts Health & Nutrition Update
 Research news you can use from the editors of the Tufts Health & Nutrition Letter.

September 30, 2013

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Plant Pigments Might Help Protect Your Bones


Natural pigments found in plants, called carotenoids, may help protect against bone loss in older men and women, according to new research led by Tufts epidemiologist Katherine Tucker, PhD.

In addition to the familiar beta-carotene, Tufts researchers and colleagues at Boston University and Hebrew SeniorLife in Boston examined potential effects on bone mineral density of carotenoids including alpha-carotene, beta-cryptoxanthin, lycopene and lutein plus zeaxanthin. The four-year study tracked changes in bone mineral density at two areas of the hip and lumbar spine of 213 men and 390 women, average age 75, participating in the Framingham Osteoporosis Study. Carotenoids, particularly lycopene, were associated with some level of protection against losses in bone mineral density at the hip in men and at the lumbar spine in women. No significant associations were observed at the other bone sites.

The results suggest there is a protective effect of carotenoids against bone loss in older adults.

 

Read Full Article 

Dark Chocolate: A Valentine for Your Health


Many foods that nutrition scientists find are good for us can be difficult to love. Think of broccoli, which the first President Bush famously refused to eat. But then there's chocolate, which study after study reports has health benefits to match its deliciousness. The only trouble with chocolate, of course, is that it's also high in calories and fat.

What's a sensible way to strike a balance between enjoying chocolate's health (and taste) benefits and minimizing its downsides? With the chocolate-giving holiday of Valentine's Day in mind, we posed that question to Jeffrey B. Blumberg, PhD, director of Tufts' HNRCA Antioxidants Research Laboratory and a noted expert on the health effects of the antioxidant polyphenol compounds found in chocolate.

"The evidence that polyphenols-specifically the flavonoids and, especially, the flavanols-in chocolate have some health benefits continues to grow," says Blumberg. "The highest concentrations of these polyphenols are found in dark chocolate. Studies have particularly focused on cardiovascular endpoints like blood pressure and vascular reactivity. Indeed, enough data has now been generated from these studies that positive results have been demonstrated in several published systematic reviews and meta-analyses

Read Full Article 

Omega-3s in Fish May Help Slow Biological Aging

 

The omega-3 fats in fish oil, touted for their heart-health benefits, may have a bonus for heart patients: slowing biological aging at the cellular level. In a study of patients with stable coronary artery disease, those with the highest blood levels of omega-3s also showed the least shortening of telomeres, a sign of biological rather than chronological aging. Patients with the lowest omega-3 levels, on the other hand, had the fastest rate of telomere shortening when researchers compared measurements from the start of the study to five years later.

Several studies have shown increased survival rates among individuals with established cardiovascular disease who consume more omega-3 fatty acids from fish. But the mechanisms underlying this protective effect are not well understood.


Telomeres are a structure at the end of a chromosome involved in the replication and stability of the chromosome. Genetic factors and environmental stresses can shorten the length of a telomere, so telomere length is becoming an emerging marker of biological age.

   

Read Full Article 

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Pediatric Anxiety Seminar - RSVP today!

 

Local NIH Event

 Pediatric Anxiety Seminar, October 10, 2013, 7 – 8:30 pm, 301-402-8225


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